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FROM ROME: Motorway for Florence, Orte exit: highway for Terni, Amelia exit. In the municipality of Amelia (50 metres after the road sign), take the first junction on the right (near the “Le Colonne” restaurant). Follow signs for Melezzole. Pass through the villages of Sambucetole, Castel dell’Aquila, Toscolano and Melezzole. The centre is about 3 km after the village of Melezzole (first junction on the right, towards Pantanelli). After Amelia, you can follow the yellow road signs for the Marc Mességué Health Center.
 
FROM MILAN: Florence-Rome motorway, Orvieto exit. Follow signs for Baschi, Montecchio and Melezzole. Before the village of Melezzole (about 2 km) turn left, following signs for Pantanelli. After Montecchio you can follow the yellow road signs for the Marc Mességué Health Center.